We are always introducing new clinical trials across our international network. If you can’t find what you are looking for please don’t hesitate to speak to your doctor to learn more, or contact us here.
Find a trial
At Icon, we offer clinical trials across various tumour types and blood disorders, allowing patients access to new and emerging advances in treatment, find a trial that might be suitable for you.
Use the search function below to find a clinical trial that may suit you and your cancer diagnosis
IL Believe
A Phase 1/2, Open-label, Dose Escalation and Dose Expansion Study to Investigate the Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab, Standard of Care Chemotherapy, or TransCon TLR7/8 Agonist, or in Combination With Pembrolizumab and Standard of Care Chemotherapy, in Adult Participants With Locally Advanced or Metastatic Solid Tumor Malignancies
Locations
Farrer Park
Diagnosis
Advanced solid tumours, Cervical cancer, Lung cancer, Skin cancer – melanoma
BA3011-002
A Phase 2 Study of BA3011 Alone and in Combination with Nivolumab in Adult Patients with Metastatic Non-Small Cell Lung Cancer Who Had Prior Disease Progression on a PD-1/L1, EGFR, or ALK Inhibitor
Locations
Central Building (Oncology)
Diagnosis
Lung cancer
Viktoria-1
A Phase 3, Open-Label, Randomized, Two-Part Study Comparing Gedatolisib in Combination with Palbociclib and Fulvestrant to Standard-of-Care Therapies in Patients with HR-Positive, HER2-Negative Advanced Breast Cancer Previously Treated with a CDK4/6 Inhibitor in Combination with Non-Steroidal Aromatase Inhibitor Therapy
Locations
Farrer Park
Diagnosis
Breast cancer
DeLLphi-306
A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter Study of Tarlatamab Therapy in Subjects With Limited-Stage Small-Cell Lung Cancer (LS-SCLC) Who Have Not Progressed Following Concurrent Chemoradiation Therapy
Locations
Mount Alvernia
Diagnosis
Lung cancer
pionERA Breast Cancer
A Phase III Randomized, Open-Label Study Evaluating Efficacy and Safety of Giredestrant Compared With Fulvestrant, Both Combined With a CDK4/6 Inhibitor, in Patients With Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer With Resistance to Prior Adjuvant Endocrine Therapy
Locations
Gleneagles, Farrer Park
Diagnosis
Breast cancer
pionERA
A Phase III Randomized, Open-Label Study Evaluating Efficacy and Safety of Giredestrant Compared With Fulvestrant, Both Combined With a CDK4/6 Inhibitor, in Patients With Estrogen Receptor-Positive, HER2-Negative Advanced Breast Cancer With Resistance to Prior Adjuvant Endocrine Therapy
Locations
Gleneagles, Farrer Park
Diagnosis
Breast cancer
INAVO122
A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo As Maintenance Therapy After First Line Induction Therapy in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer
Locations
Farrer Park
Diagnosis
Breast cancer
CAMBRIA-1
A Phase III, Open-Label, Randomised Study to Assess the Efficacy and Safety of Extended Therapy With Camizestrant Versus Standard Endocrine Therapy (Aromatase Inhibitor or Tamoxifen) in Patients With ER+/HER2- Early Breast Cancer
Locations
Farrer Park
Diagnosis
Breast cancer
STELLAR 303
A Randomized Open-Label Phase 3 Study of XL092 + Atezolizumab vs Regorafenib in Subjects With Metastatic Colorectal Cancer
Locations
Farrer Park
Diagnosis
Colorectal cancer
Relativity-106
A Study of Nivolumab and Relatlimab in Combination With Bevacizumab in Advanced Liver Cancer (RELATIVITY-106)
Locations
Farrer Park
Diagnosis
Liver cancer
ABCPro
ABCPro: Trial is evaluating a new online service for managing self-reported symptoms by people with advanced breast cancer
Locations
Bowen Icon Cancer Centre
Diagnosis
Breast cancer
ALLG NBCR
ALLG NBCR: Australasian Leukaemia and Lymphoma Group National Blood Cancer Registry
Locations
Wesley
Diagnosis
Leukaemia
AMLM22/D1
AMLM22/D1: The International Acute myeloid leukaemia (AML) Platform Consortium (IAPC) trial is a randomised, multi-arm study platform to compare the efficacy of experimental therapies versus standard of care in patients with acute myeloid leukaemia in first complete remission
Locations
South Brisbane, Wesley, Chermside, Southport
Diagnosis
Leukaemia
AMT-116-01
AMT-116-01: AMT-116 in Patients With Advanced Solid Tumors
Locations
South Brisbane
Diagnosis
Advanced solid tumours
AMT-151-01
AMT-151-01: AMT-151 in Patients With Selected Advanced Solid Tumours
Locations
South Brisbane
Diagnosis
Advanced solid tumours
AMT-253-01
AMT-253-01: AMT-253 in Patients With Selected Advanced Solid Tumours
Locations
South Brisbane
Diagnosis
Advanced solid tumours
REGENERON_ R1979-ONC-1625
An open-label study to assess the anti-tumor activity and safety of REGN1979, an Anti-CD20 X Anti-CD3 bispecific antibody, in patients with relapsed or refractory B-cell non-hodgkin lymphoma
Locations
Farrer Park
Diagnosis
Lymphoma – B-cell Non Hodgkin’s
ANZadapt / ANZUP 2101
ANZadapt / ANZUP 2101: Phase II Randomised Controlled Trial of Patient-specific Adaptive vs. Continuous Abiraterone or eNZalutamide in mCRPC
Locations
Adelaide (Kurralta Park)
Diagnosis
Prostate cancer
ARC-20
ARC-20: A Phase 1 Study of AB521 Monotherapy and Combination Therapies in Renal Cell Carcinoma and Other Solid Tumors
Locations
Adelaide (Kurralta Park)
Diagnosis
Advanced solid tumours
ASPEN-06 / AT148006
ASPEN-06 / AT148006: A Study of Evorpacept (ALX148) in Patients with Advanced HER2+ Gastric Cancer
Locations
Southport
Diagnosis
Gastric / gastroesophageal cancer
ASPIRE / CL-SBP-101-04
ASPIRE / CL-SBP-101-04: Study of Nab-Paclitaxel and Gemcitabine With or Without SBP-101 in Pancreatic Cancer
Locations
Adelaide (Kurralta Park)
Diagnosis
Pancreatic cancer
AWT020-001
AWT020-001: Phase 1 Study of AWT020 in Advanced Cancer
Locations
South Brisbane
Diagnosis
Advanced solid tumours
BBI-TP-3654-102
BBI-TP-3654-102: A Study of Oral Nuvisertib (TP-3654) in Patients with Myelofibrosis
Locations
Adelaide (Windsor Gardens)
Diagnosis
Myeloproliferative disorders
BG-C137-101
BG-C137-101: A First-in-Human Study of BG-C137, an Anti-FGFR2b Antibody Drug Conjugate, in Participants With Advanced Solid Tumors
Locations
South Brisbane
Diagnosis
Advanced solid tumours
BGB-24714-101
BGB-24714-101: A Study of BGB-24714 as Monotherapy and With Combination Therapies in Participants With Solid Tumors
Locations
South Brisbane
Diagnosis
Advanced solid tumours
BGB-3111-LTE1
BGB-3111-LTE1: Long-term Extension Study of Zanubrutinib (BGB-3111) Regimens in Participants With B-cell Malignancies
Locations
Wesley
Diagnosis
B-cell malignancies
BGB-A317-26808-101
BGB-A317-26808-101: A Study Investigating BGB-26808 Alone or in Combination With Tislelizumab in Participants With Advanced Solid Tumors
Locations
Adelaide (Kurralta Park)
Diagnosis
Advanced solid tumours
BGB-A317-A3055-101
BGB-A317-A3055-101: A Study of BGB-A3055, Alone and in Combination With Tislelizumab in Participants With Selected Advanced or Metastatic Solid Tumors
Locations
South Brisbane
Diagnosis
Advanced solid tumours
BGB-A317-LBL-007-201
BGB-A317-LBL-007-201: A Study Investigating the Efficacy and Safety of LBL-007 Plus Tislelizumab in Combination With Bevacizumab Plus Fluoropyrimidine Versus Bevacizumab Plus Fluoropyrimidine in Participants With Unresectable or Metastatic Colorectal Cancer
Locations
South Brisbane
Diagnosis
Colorectal cancer
BM230-01
BM230-01: Study of BM230 in Patients With Advanced Solid Tumors
Locations
South Brisbane
Diagnosis
Advanced solid tumours
BNT327-02
BNT327-02: Safety and Preliminary Effectiveness of BNT327, an Investigational Therapy for Breast Cancer, When Given in Combination with Chemotherapy
Locations
Wesley
Diagnosis
Breast cancer
BRIGHTLINE-2 / 1403-0011
BRIGHTLINE-2 / 1403-0011: A Study to Test Whether Brigimadlin (BI 907828) Helps People With Cancer in the Biliary Tract, Pancreas, Lung or Bladder
Locations
South Brisbane
Diagnosis
Advanced solid tumours
C2321014
C2321014: A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1)
Locations
Wesley
Diagnosis
Prostate cancer
C4391022
C4391022: A Study to Learn About the Study Medicine Called PF-07220060 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment
Locations
Townsville
Diagnosis
Breast cancer
CLINCH / ATG-022-ST-001
CLINCH / ATG-022-ST-001: A Study of ATG-022 in Patients With Advanced/Metastatic Solid Tumors
Locations
South Brisbane
Diagnosis
Advanced solid tumours
DB-1303-O-1001
DB-1303-O-1001: A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors
Locations
South Brisbane
Diagnosis
Advanced solid tumours
DCC-3116-01-001
DCC-3116-01-001: A Phase 1/2 Study of DCC-3116 in Patients With RAS/MAPK Pathway Mutant Solid Tumors
Locations
Adelaide (Kurralta Park)
Diagnosis
Advanced solid tumours
DECREASE
DECREASE: Darolutamide + Consolidation Radiotherapy in Advanced Prostate Cancer Detected by PSMA
Locations
Epworth Richmond
Diagnosis
Prostate cancer
DM001001
DM001001: A Study of DM001 in Patients With Advanced Solid Tumors
Locations
South Brisbane
Diagnosis
Advanced solid tumours
DM005001
DM005001: A Study of DM001 in Patients With Advanced Solid Tumors
Locations
South Brisbane
Diagnosis
Advanced solid tumours
Duravelo-2 / BT8009-230
Duravelo-2 / BT8009-230: Study BT8009-230 in Participants With Locally Advanced or Metastatic Urothelial Cancer
Locations
Wesley
Diagnosis
Urothelial cancer
EG-70-101
EG-70-101: LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve
Locations
Adelaide (Kurralta Park)
Diagnosis
Bladder cancer
ERUPT
ERUPT: Urethral scarring after radiation treatment for prostate cancer
Locations
Toowoomba
Diagnosis
Prostate cancer
EvoPAR-Prostate01 / D9723C00001
EvoPAR-Prostate01 / D9723C00001: Saruparib (AZD5305) vs Placebo in Men With Metastatic Castration-Sensitive Prostate Cancer Receiving Physician’s Choice New Hormonal Agents
Locations
Chermside, Townsville, Adelaide (Kurralta Park)
Diagnosis
Prostate cancer
EXPERT / ANZ1601
EXPERT / ANZ1601: EXamining PErsonalised Radiation Therapy for Low-risk Early Breast Cancer
Locations
Epworth Richmond
Diagnosis
Breast cancer
FIG
FIG: Prospective, multicentre trial evaluating O-(2-[18F]-fluoroethyl)-L-tyrosine Positron Emission Tomography in Glioblastoma (FET-PET in Glioblastoma)
Locations
Wesley
Diagnosis
Brain cancer
HARMONY / R3767-ONC-2011
HARMONY / R3767-ONC-2011: Clinical Study of Fianlimab in Combination With Cemiplimab Versus Pembrolizumab in Adolescent and Adult Patients With Previously Untreated Unresectable Locally Advanced or Metastatic Melanoma
Locations
Hobart
Diagnosis
Skin cancer – melanoma
HERTHENA-PanTumor01 / U31402-277
HERTHENA-PanTumor01 / U31402-277: A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Locations
Chermside, Hobart
Diagnosis
Advanced solid tumours
HLX10-020-SCLC302
HLX10-020-SCLC302: A Study to Evaluate the Efficacy and Safety of Serplulimab in Combination With Chemotherapy and Concurrent Radiotherapy in Patients With Limited-Stage Small Cell Lung Cancer
Locations
Wesley
Diagnosis
Lung cancer
HMDB-001-002
HMDB-001-002: Study of an Anti-HER3 Antibody, HMBD-001, With or Without Chemotherapy in Patients With Solid Tumors Harboring an NRG1 Fusion or HER3 Mutation
Locations
South Brisbane
Diagnosis
Advanced solid tumours
HX044-I-01
HX044-I-01: HX044, FIH Study in Patients With Advanced Solid Tumor Malignancies
Locations
Wesley
Diagnosis
Advanced solid tumours
I-MAT / MASC 03.18
I-MAT / MASC 03.18: Immunotherapy Adjuvant Trial in Patients with Stage I-III Merkel Cell Carcinoma
Locations
Hobart
Diagnosis
Skin cancer – non-melanoma
J2N-MC-JZNX
J2N-MC-JZNX: A Study Evaluating the Efficacy and Safety of Pirtobrutinib in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Locations
Adelaide (Kurralta Park)
Diagnosis
Leukaemia
JSKN033-101
JSKN033-101: JSKN033 in Patients With Advanced or Metastatic Solid Malignant Tumors
Locations
Wesley
Diagnosis
Advanced solid tumours
KATRINA
KATRINA: Pembrolizumab (KeytrudA) in early Triple Negative breast cancer in Australia
Locations
Wesley, Hobart
Diagnosis
Breast cancer
LIBERATE
LIBERATE: Clinical registry of focal low dose rate brachytherapy in men with biopsy confirmed low-intermediate risk prostate cancer
Locations
Epworth Richmond, Epworth Freemasons, Geelong
Diagnosis
Prostate cancer
LINKER-MM3 / R5458-ONC-2245
LINKER-MM3 / R5458-ONC-2245: A Trial to Learn How Well Linvoseltamab Works Compared to the Combination of Elotuzumab, Pomalidomide and Dexamethasone for Adult Participants With Relapsed/Refractory Multiple Myeloma
Locations
Wesley
Diagnosis
Multiple myeloma
LOXO-ENC-23001 / J5A-OX-JZWA
LOXO-ENC-23001 / J5A-OX-JZWA: A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors
Locations
Adelaide (Kurralta Park)
Diagnosis
Advanced solid tumours
LOXO-FRA-24001 / J5E-OX-JZXA
LOXO-FRA-24001 / J5E-OX-JZXA: A Study of LY4170156 in Participants With Selected Advanced Solid Tumors
Locations
South Brisbane
Diagnosis
Advanced solid tumours
LUNA / CP-MGC026-01
LUNA / CP-MGC026-01: A Study of MGC026 in Participants With Advanced Solid Tumors
Locations
Adelaide (Kurralta Park), Wesley
Diagnosis
Advanced solid tumours
Lunar-2
LUNAR-2: Pivotal, Randomized, Open-Label Study of Tumor Treating Fields (TTFields, 150 kHz) Concomitant with Pembrolizumab and Platinum Based Chemotherapy for the Treatment of Metastatic Non-Small Cell Lung Cancer
Locations
Farrer Park, Mount Alvernia
Diagnosis
Lung cancer
MASTERPLAN / CTC 0245
MASTERPLAN / CTC 0245: MFOLFIRINOX And Stereotactic Radiotherapy (SBRT) for Pancreatic Cancer With High Risk and Locally Advanced Disease
Locations
Gold Coast University Hospital
Diagnosis
Pancreatic cancer
MRDR
MRDR: Myeloma and Related Disease Registry
Locations
Wesley, Adelaide (Kurralta Park)
Diagnosis
Multiple myeloma
MTX-GPC3-303
MTX-GPC3-303: A Study of MT-303 in Adults With Advanced or Metastatic GPC3-Expressing Cancers, Including HCC
Locations
South Brisbane
Diagnosis
Advanced solid tumours
OLYMPIA-1 / R1979-HM-2298
OLYMPIA-1 / R1979-HM-2298: A Trial to Learn if Odronextamab is Safe and Well-Tolerated and How Well it Works Compared to Rituximab Combined With Different Types of Chemotherapy for Participants With Follicular Lymphoma
Locations
Wesley
Diagnosis
Lymphoma – B-cell Non Hodgkin’s
OLYMPIA-3 / R1979-ONC-2105
OLYMPIA-3 / R1979-ONC-2105: A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Patients With Previously Untreated Diffuse Large B-cell Lymphoma
Locations
Wesley
Diagnosis
Lymphoma – B-cell Non Hodgkin’s
OPTIMA / BCT 2202
OPTIMA / BCT 2202: Optimal personalised treatment of early breast cancer using multiparameter analysis
Locations
Southport, Wesley, Hobart, Adelaide (Kurralta Park)
Diagnosis
Breast cancer
PRIME_LUNG
PRIME_LUNG: Primary Radiotherapy In MEtastatic Lung Cancer – A Pilot Study
Locations
Gold Coast University Hospital
Diagnosis
Lung cancer
Q-IMPROvE
Q-IMPROvE: Whole genome sequencing in high risk breast cancer patients
Locations
Wesley
Diagnosis
Breast cancer
RAMP 301 / VS-6766-301
RAMP 301 / VS-6766-301: A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serious Ovarian Cancer
Locations
Wesley
Diagnosis
Ovarian cancer
REFRaME-01 / STRO-002-GM3
REFRaME-O1 / STRO-002-GM3: A Study to Investigate the Efficacy and Safety of Luveltamab Tazevibulin Versus Investigator’s Choice (IC) Chemotherapy in Women With Ovarian Cancer (Including Fallopian Tube or Primary Peritoneal Cancers) Expressing FOLR1
Locations
Wesley
Diagnosis
Ovarian cancer
ROSEND
ROSEND: A Randomised trial for the treatment of recalcitrant symptomatic rosacea using definitive volumetric modulated arc radiotherapy or standard dermatological treatment
Locations
Revesby, Gosford
Diagnosis
Skin cancer – non-melanoma
SB221
SB221: Combination of SON-1010 (IL12-FHAB) and Atezolizumab in Patients With Platinum-resistant Ovarian Cancer
Locations
Adelaide (Kurralta Park)
Diagnosis
Ovarian cancer
SCTB14-X101
SCTB14-X101: Aims to Explore the Safety, Tolerability, and Preliminary Efficacy of SCTB14 in Adult Patients With Advanced Malignant Solid Tumours
Locations
South Brisbane
Diagnosis
Advanced solid tumours
SGNDV-001
SGNDV-001: Disitamab Vedotin With Pembrolizumab vs Chemotherapy in Previously Untreated Urothelial Cancer Expressing HER2
Locations
Chermside
Diagnosis
Urothelial cancer
SHR-4602-102
SHR-4602-102: A Trial of SHR-4602 Infusion in Patients With SHR-4602 in Subjects With HER2-expressing or HER2-mutated Locally Advanced or Metastatic Solid Tumors
Locations
South Brisbane
Diagnosis
Advanced solid tumours
SLN124-004
SLN124-004: Study to Assess SLN124 in Patients With Polycythemia Vera
Locations
Adelaide (Kurralta Park)
Diagnosis
Myeloproliferative disorders
STARSTRUCK / 177Lu-TLX250-001
STARSTRUCK / 177Lu-TLX250-001: Combination of 177Lu-TLX250 and Peposertib in Patients With Carbonic Anhydrase IX -Expressing Solid Tumors
Locations
Adelaide (Kurralta Park)
Diagnosis
Advanced solid tumours
STELLAR-304 / XL094-304
STELLAR-304 / XL094-304: Study of XL092 + Nivolumab vs Sunitinib in Subjects With Advanced or Metastatic Non-Clear Cell Renal Cell Carcinoma
Locations
Chermside
Diagnosis
Cancer-unknown origin
SUNRAY-01 / J3M-MC-JZQB
SUNRAY-01 / J3M-MC-JZQB: A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer
Locations
Wesley
Diagnosis
Lung cancer
TRACIE / CO-AU-979-6695
TRACIE / CO-AU-979-6695: TRodelvy use in AdvanCed TrIple Negative BrEast Cancer in Australia
Locations
Townsville, Hobart, Adelaide (Kurralta Park)
Diagnosis
Breast cancer
TREMOR
TREMOR: Safety and effectiveness of frameless linac-based stereotactic radiosurgery on tremor in patients with essential tremor or Parkinson’s disease
Locations
Epworth Richmond
Diagnosis
Neurological conditions
TUGETHER / BCT2102
TUGETHER / BCT 2102: Tucatinib Together With Pembrolizumab and Trastuzumab
Locations
Hobart
Diagnosis
Breast cancer
VELOCITY-HNSCC / GS-US-699-7184
VELOCITY-HNSCC / GS-US-699-7184: Study of Novel Treatment Combination Therapies in Participants with Head and Neck Squamous Cell Carcinoma
Locations
Adelaide (Kurralta Park)
Diagnosis
Head and neck cancer
VIKTORIA-1 / CELC-G-301
VIKTORIA-1 / CELC-G-301: Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer
Locations
Southport
Diagnosis
Breast cancer
VVD-130850-01
VVD-130850-01: A First-in-Human (FIH) Study to Evaluate the Safety and Tolerability of VVD-130850 in Participants With Advanced Solid and Hematologic Tumors
Locations
South Brisbane
Diagnosis
Advanced solid tumours
WOMBAT / ANZUP 2201
WOMBAT / ANZUP 2201: Evaluating the efficacy of bipolar androgen therapy in extending metastasis-free survival in patients with M0 castrate-resistant prostate cancer with prostate specific antigen progression but not radiological or clinical progression on darolutamide
Locations
Chermside
Diagnosis
Prostate cancer
X4P-001-110
X4P-001-110: A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections
Locations
Southport
XPORT-EC-042
XPORT-EC-042: Selinexor in Maintenance Therapy After Systemic Therapy for Participants with P53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma
Locations
Southport
Diagnosis
Endometrial cancer
ZN-c3-004
ZN-c3-004: A Study of ZN-c3 in Women With Recurrent or Persistent Uterine Serous Carcinoma
Locations
Chermside
Diagnosis
Endometrial cancer
ZN-c3-005
ZN-c3-005: A Study of ZN-c3 in Subjects With High-Grade Serous Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Locations
Chermside
Diagnosis
Ovarian cancer